BerbamunineおよびそのDiastereoisomerの全合成 : 複素環式化合物の合成研究第254報

抄録

Hydrolysis of O, O, O-tribenzylberbamunine type compounds, which were obtained by Ullmann reaction of l-7, 4'-O, O-dibenzyl-3'-bromo-N-methylcoclaurine (VI) with d-7-benzyl-N-methylcoclaurine (VII) and l-VII, gave berbamunine (I) and the compound (IX), respectively. Methylation of the latter compound (IX) with diazomethane gave O-methyldauricine. On the other hand, the same methylation of the former optically active berbamunine (I) afforded O, O, O-trimethylberbamunine (III).