4-ヨードチモールの定量法の研究(第4報) : ポーラログラフによる定量
1969 年 89 巻 1 号 p. 79-83
詳細
1969 年 89 巻 1 号 p. 79-83
Polarographic determination of 4-iodothymol was studied. Potassium chloride and tetraethylammonium bromide were used as supporting electrolytes. In the case of potassium chloride a wave owing to nonfaradaic current was obtained at about -1.2 V (vs.Hg pool), and the limiting current of this wave was not proportional to the 4-iodothymol concentration. On the other hand, in a tetraethylammonium bromide solution, a well-defined wave which was attributed to the reduction of 4-iodothymol was obtained at around -1.6 V (vs. Hg pool). The limiting current of this wave was proportional to the 4-iodothymol concentration and to the square root of Hg column height. The temperature coefficient for wave-height was 1.7% deg-1. These facts show that 4-iodothymol is reduced under the control of diffusion. 4-Iodothymol can be polarographically determined in the concentration range of 0.05 to 0.5 mg/m1. 4-Iodothymol in drugs was extracted with petroleum ether and determined with good accuracy by this method.
