YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
溶解補助剤の研究(第1報) : グリコール類およびその誘導体と水との混液の溶存酵素について
加藤 百合子泉 京子坂庭 康夫塩山 秀寿青木 治代
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1969 年 89 巻 9 号 p. 1297-1301

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Measurement of dissolved oxygen was carried out by the carbon dioxide evolution method and by gas chromatography on various concentrations of mixtures of nine kinds of solubilizing agent and water. In mixtures of ethylene glycol, diethylene glycol, triethylene glycol-H2O, having a hydrophilic group, and water, dissolved oxygen was found to decrease with increasing concentration of these agents. In contrast, aqueous mixtures of Cellosolve, Butyl Cellosolve, Carbitol, Butyl Carbitol, hexylene glycol, dipropylene glycol-H2O, having both hydrophilic and hydrophobic groups, showed a minimum point in the content of dissolved oxygen, and its amount increased above that point, and the agents alone, without the presence of water, was found to have the largest content of oxygen. In these mixtures, function of the solution to dissolve oxygen decreased at the concentration of the minimum point.

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© by the PHARMACEUTICAL SOCIETY OF JAPAN
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