YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
Maltol Glucosideから N-置換-3-glucosyloxy-2-methyl-4-pyridone類およびN-置換-3-hydroxy-2-methyl-4-pyridone類の合成
安江 政一河村 典久榊原 仁作
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1970 年 90 巻 10 号 p. 1222-1225

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N-Substituted 3-glucosyloxy-2-methyl-4-pyridones were synthesized from natural maltol glucoside (III) and primary amines. Aliphatic amines reacted readily with (III) in aqueous methanol under reflux, while aromatic amines required the addition of potassium hydroxide as a catalyst. The aglycones, N-substituted 3-hydroxy-2-methyl-4-pyridones, were obtained by acid hydrolysis of the above pyridone glucosides.

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© by the PHARMACEUTICAL SOCIETY OF JAPAN
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