ベンゾヘテロ環化合物の研究(第8報) : インドリン誘導体の合成ならびに薬理作用 その1
1970 年 90 巻 12 号 p. 1524-1531
詳細
1970 年 90 巻 12 号 p. 1524-1531
In order to examine antiphlogistic-analgesic activity of indoline derivatives, 3-[ω-(N, N-dialkyl)aminoalkyl]-3-methyl-1-phenyl-(I) and 3-[ω-(N, N-dialkyl)aminoalkoxy]-3-methyl-1-phenyl-indolin-2-one (II), and their related compounds were synthesized. Among these, 28 compounds were tested for their inhibitory action on writhing syndrome produced by acetic acid, their effect on general behavior, and their acute toxicity.
