トランス-π-オキソカンファーの代謝(第2報) : 経口投与時の代謝

抄録

The metabolites in the human urine after the administration of trans-π-oxocamphor (I) were examined by changing the administration formula. Main metabolites in the urine after oral administration of I were trans-π-hydroxycamphor glucuronide (II-G) (70%), trans-π-apocamphor-7-carboxylic acid (III) (5%), and its glucuronide (III-G) (25%), while those after subcutaneous a dministration were II-G (trace), III (30%), and III-G (70%). The absorption of I through oral cavity membrane was also examined.