YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
Acetamido-azabenzobicyclo[3,3,1]nonane類の合成 : 中枢性鎮痛剤の化学構造と薬理作用の関係に関する研究(第12報)(有機化学)
塩谷 俊作三橋 監物
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1972 年 92 巻 1 号 p. 97-100

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Acetamide derivatives of benzomorphans and 1, 3-dimethyl-1, 2, 3, 4, 5, 6-hexahydro-1, 5-methano-3-benzazocine were synthesized in order to examine the pharmacological effect of the acetamide group. The stereochemical pathways in the catalytic reduction of the oximes (II-A, II-B, II-C) with hydrogen and the Adams catalyst under several conditions were discussed.

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© by the PHARMACEUTICAL SOCIETY OF JAPAN
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