1973 年 93 巻 1 号 p. 119-123
1) Accumulation of cadmium and its effect on various organs of the rat was discussed. 2) During the first week of daily intraperitoneal administration of cadmium chloride, body weight of rats decreased and then it increased in spite of repeated injection. 3) Most of cadmium given by intraperitoneal administration accumulated in the liver and kidney, but not in the brain. 4) After intraperitoneal administration of cadmium chloride, non-protein-bound sulfhydryl content decreased in the liver, while protein-bound sulfhydryl content increased in the kidney. 5) Changes in the fatty acid composition by cadmium administration were not observed in various organs of the rat.