YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
Quinazolineに対するReformatsky反応
東野 武郎鷲巣 哲治林 英作
著者情報
ジャーナル フリー

1973 年 93 巻 9 号 p. 1234-1235

詳細
抄録

α-Haloesters reat with carbonyl compounds like aldehydes, ketones, and esters, in the presence of zinc, to form β-hydroxy esters, the so-called Reformatsky reaction, which was said to be limited to the foregoing carbonyl compounds. In the present series of work, quinazoline was taken up in place of carbonyl compounds and the Reformatsky reaction of quinazoline with ethoxycarbonylmethylzinc bromide was carried out. The reaction progressed and ethyl 4-quinazolioeacetate was formed, though in a low yield, and formation route of this compound was considered.

著者関連情報
© by the PHARMACEUTICAL SOCIETY OF JAPAN
前の記事 次の記事
feedback
Top