YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
Studies on Chemical Analysis by Measurement of Reaction Rate. II. Conductivity Method for Determination of Urea by Using Urease
SHOICHIRO TAGAMIAYAKO MATSUBATERUKO SAWADATAKU NAKANODEN-ITSU SHIHO
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1974 Volume 94 Issue 11 Pages 1384-1388

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Abstract
An acurate and rapid method has been developed for the determination of urea based on the measurement of the electric conductivity of ammonium carbonate produced from urea by urease in solution. The initial decomposition rates were followed by recording the response signal related to the change of electric conductivity as a function of time. This simple method is also applicable to samples containing NH4+ or other ions. It is well suited for routine analysis, such as determination of urea in urine and fertilizers.
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© by the PHARMACEUTICAL SOCIETY OF JAPAN
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