1974 年 94 巻 3 号 p. 351-358
Some 1, 3-disubstituted 1, 2, 3, 4-tetrahydro-β-carboline derivatives were synthesized by the Pictet-Spengler reaction with DL-tryptophan methyl ester and aldehydes. They were separated into their stereoisomers by alumina column chromatography, and their configuration (cis and trans) was examined from their nuclear magnetic resonance spectra and those of their acetates. By the application of the above result, azoninoindole derivatives (11 and 12) were synthesized.