1974 年 94 巻 5 号 p. 593-601
Determination of 13 kinds of sulfanilamides was attempted by thermometric and differential thermometric titrations, and heat of reaction was also calculated. Quantitative determination was made by the diazotization method using sodium nitrite and by the neutralization method using sodium hydroxide. Diazotization method by thermometric titration made it possible to determine at ordinary temperature, without the use of an indicator, and the error was within 3% to less than 0.5%. In the case of neutralization method, determination with an error of within 3% was possible by the use of 50% (v/v) acetone-water as a solvent and by slow titration speed.