複素環化合物の研究(第3報)2-(2,6-Dichlorobenzylidenehydrazino)-1,4,5,6-tetrahydropyrimidine Hydrochlorideおよび関連化合物の合成
1975 年 95 巻 11 号 p. 1271-1282
詳細
1975 年 95 巻 11 号 p. 1271-1282
An antihypertensive agent, 2-(2, 6-dichlorobenzylidenehydrazino)-1, 4, 5, 6-tetrahydropyrimidine hydrochloride (OT-24), was obtained by the nuclear reduction of 2-(2, 6-dichlorobenzylidenehydrazino)pyrimidine using palladium-carbon catalyst in acid solution. A number of new tetrahydropyrimidines containing benzylidenehydrazino and benzylhydrazino substituents were synthesized together with several related compounds.
