YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
水晶体カプセルの膜電位と膜透過係数に対する上皮の影響
中垣 正幸宮田 堅司
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1975 年 95 巻 3 号 p. 285-289

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Eye-lens capsule has one layer of epithelium inside its anterior part and this lens epithelium is said to play an important role in active transport. Therefore, the membrane potential and the membrane permeability coefficient of the epithelium-capsule were compared with those of the capsule whose epithelium was taken off in distilled water. Measurement of membrane potential of the capsule and the epithelium-capsule showed that the capsule is a positively charged membrane and that the epithelium-capsule is a negatively charged membrane, and that charge density of the latter is four or five times larger than that of the former in the absolute value. It was also found that the reduced permeability coefficient of the epithelium-capsule is considerably smaller than that of the capsule, although the permeability coefficient is about the same value for both membranes with and without the epithelium at sufficiently high electrolyte concentration.

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© by the PHARMACEUTICAL SOCIETY OF JAPAN
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