Fumariline型塩基のマススペクトルについて(第1報)C環上のアルコオキシ基の位置とそのマススペクトルの関係および中間体法を用いた開裂機構

抄録

The mass spectrometric fragmentation pattern of 21 kinds of fumariline alkaloids of the spirobenzylisoquinoline type was studied. All of the compounds examined were classified into three groups according to the alkoxy substituent pattern on the ring-C, the first group consists of the compounds having alkoxy groups in 9- and 10-positions, the second one at 11- and 12-positions, and the third one at 10- and 11-positions. The compounds of the first and third groups exclusively exhibited the base peak of (M-29), while the second group compounds showed the base peak at (M-59). The fragmentation mechanism has been proposed from the evidence that the mass spectra of appropriate aporphine alkaloids were closely related with those of fumariline-type alkaloids, and the mechanism was suported by the accompanying metastable ions.