YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
4-Amino-および4-Hydroxyaminoquinoline 1-Oxide関連化合物とPOCl3との反応
沢西 啓之神谷 庸
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1976 年 96 巻 6 号 p. 725-731

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The reaction 4-aminoquinoline 1-oxide (4-AQO) or 4-hydroxyaminoquinoline 1-oxide (4-HAQO) with POCl3, and its mechanism were examined, and it was found that the reaction of 4-AQO, 4-HAQO, or their derivatives with POCl3 afforded the corresponding 3-chloro compound as the main product. A reaction mechanism was proposed for the formation of the 3-chloro compound from 4-AQO and 4-HAQO.

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© by the PHARMACEUTICAL SOCIETY OF JAPAN
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