エストロン-6,7-³Hのモルモットのおける代謝

抄録

After intraperitoneal injection of estrone[6, 7-³H] into guinea pigs, its urinary metabolites were measured by reverse isotope dilution method. The formation of 2-hydroxyestrone and 2-methoxyestrone was observed in male and female animals. The conversion of radioactive estrone to estradiol was found to be negligible. No other metabolites were found.