N-モノ置換Diphenylphosphinamide類のアルキル化反応

抄録

A facile preparative method for N, N-disubstituted diphenylphosphinamides was developed. Treatment of N-alkyl (or phenyl) diphenylphosphinamides with a slight excess of sodium hydride followed by a reaction with alkyl halides produced the corresponding N, N-disubstituted derivatives in a fair yield. It is suggested that this method of N-alkylation provides a potentially useful means for the conversion of primary amines to secondary amines.