抄録
Three urinary metabolites in rabbits administered with 5-(4-oxo-Δ2-cyclohexenyl)-5-allylbarbituric acid (oxo-Δ2-CAB) were isolated by column chromatography on Amberlite XAD-2 resin and on silica gel. Two of these were identified by direct comparison with authentic samples as 5-(4-hydroxy-Δ2-cyclohexenyl)-5-allylbarbituric acid (OH-Δ2-CAB) and unchanged oxo-Δ2-CAB. The remaining metabolite was presumed as 5-(4-hydroxycyclohexyl)-5-allylbarbituric acid (OH-CHAB) by spectral and elementary analysis data.
