生物活性を有する天然物の分離研究(第4報)木槿皮中の抗糸状菌性成分について

抄録

As one of studies on isolation of naturally occurring biologically active principles, antifungal constituents in the bark of Hibiscus syriacus L. were examined. Two active principles, oil (A), and (B), mp 156-157°, C₁₄H₈N₂O, were isolated by a suitable combination of counter-current distribution and column chromatography. It was found that A was a mixture of lauric, myristic, and palmitic acid, and B was canthin-6-one (6H-indolo [3, 2, 1-d, e] [1, 5] naphthyridin-6-one).