抄録
Cyclization of diethyl N-(5-indazolyl) aminomethylenemalonates gave ethyl 6, 9-dihydro-9-oxo-3H-pyrrolo [4, 3-f] quinoline-8-carboxylates, alkylation of which followed by hydrolysis afforded a variety of N6-substituted pyrazolo [4, 3-f] quinoline-8-carboxylic acids in a good yield. N6-Substituted pyrazolo [3, 4-f] quinoline-8-carboxylic acids were also obtained from ethyl 6, 9-dihydro-9-oxo-1H-pyrazolo [3, 4-f] quinoline-8-carboxylate in the same way. These compounds were synthesized in order to evaluate their antimicrobial activity.
