フィッシャー・インドール閉環反応とその関連化合物の研究(第13報)シフト試薬を用いたインドール-2-カルボン酸エステル誘導体の核磁気共鳴スペクトルの測定とその応用

抄録

Proton magnetic resonance spectra of several ethyl indole-2-carboxylate derivatives in the presence of a shift reagent, tris (dipivalomethanato)-europium [Eu (DPM)₃], were measured in CDCl₃ and good straight lines were obtained on plotting induced shift vs. concentration of Eu (DPM)₃ for each signal. Application of the McConnell-Robertson equation to interpret pseudocontact shifts of the indole derivatives gave good agreement between measured and predicted shifts. The relationship between substituents of indoles and the position of the co-ordinated Eu atom is discussed.