抄録
As was suggested in the first report of this series of work (Okamoto, 1959a), the CM resistance of E. coli may depend, at least partly, on the permeability of the resistant cell. Our CM resistant strains of E. coli are also non-specifically resistant to penicillin (Pn), chlortetracyline (AM) and erythromycin (EM) . If CM resistance originates from the non-specific impermeability of the resistant cells and, consequently, some alterations have occurred on the surface of such cells, influences on the resistance to CM and on those to three other drugs should be concomitant with each other. Attempts were made, therefore to test whether or not sensitivities will be altered more or less simultaneously, when the resistant cells convert to a form of the protoplast. Glycine treated protoplast was used in this report.
