Japanese Journal of Medical Science and Biology
Online ISSN : 1884-2828
Print ISSN : 0021-5112
ISSN-L : 0021-5112
A CONSIDERATION TO IMMUNE DOSES OF STAPHYLOCOCCAL ENTEROTOXIN B TO RABBITS
KUNIHIRO SHINAGAWAMASANORI ISHIBASHIHIROYUKI YAMAMOTONOBUHARU KUNITAKAZUO HISAGENJI SAKAGUCHI
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1974 Volume 27 Issue 6 Pages 309-314

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Abstract

Immune doses of staphylococcal enterotoxin B to rabbits were studied by comparing the efficiency of various immunization schedules. It was experienced that even two subcutaneous injections each with such a small dose as 10μg of enterotoxin B, the primary one with Freund's complete adjuvant and a booster one without adjuvant, could stimulate a rabbit to develop the antibody to a satisfactorily high titer determined by agar gel diffusion and passive hemagglutination.

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