麻痺性貝毒サキシトキシン類の全合成

抄録

Saxitoxin, a paralytic shellfish poison, is potent neurotoxin characterized by highly functionalized architecture including bis-guanidinium and oxygenated pyrrolidine. Recent total syntheses of saxitoxin and its analogue by Du Bois and Nagasawa groups are discussed on this mini review.