一重項酸素を用いた有機合成

–大量合成を目指したアプローチ–

抄録

Novel approaches on application of singlet oxygen for scale-up manufacturing are introduced. Instead of traditional conditions using gaseous oxygen and light, disproponation of hydrogen peroxide by molibdate ion allows in situ generation of singlet oxygen. Combination of the traditional method with microreactor also enables efficient scale-up. Details of these reports including key safety issues are discussed below.