有機合成化学協会誌
Online ISSN : 1883-6526
Print ISSN : 0037-9980
Review de Debut
配位子修飾による希土類錯体の高次イメージング機能化
伊藤 宏
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ジャーナル オープンアクセス

2012 年 70 巻 3 号 p. 276-277

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DOTA(1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid) forms thermodynamically stable and kinetically inert complexes with various lanthanide cations, and its gadolinium complex is widely employed as an MR (magnetic resonance) imaging agent. Although various lanthanide complexes have recently been developed as MR imaging contrast agents, this short review focuses on the chemical functionalizations of the DOTA-lanthanide complexes in the developments of advanced MR imaging applications.

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© 2012 社団法人 有機合成化学協会
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