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有機合成化学協会誌
Vol. 70 (2012) No. 7 p. 756-757

記事言語:

http://doi.org/10.5059/yukigoseikyokaishi.70.756

Review de Debut

Trifluoromethyl group is one of the important groups in medicinal chemistry. In 2010, Yu and Sanford reported the Pd-catalyzed aromatic C-H bond trifluoromethylation with the aid of directing groups. With these reports as a turning point, the studies on this field have been developed in a couple of years. This review describes the recent advances in aromatic C-H bond trifluoromethylation catalyzed/mediated by transition metal reagents.

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