2014 年 72 巻 1 号 p. 72-73
(−)-Actumine A is a tetracyclic alkaloid isolated from the roots of Sinomenium acutum. (−)-Actumine A possesses selective T-cell cytotoxicity, antiamnesic activity, and characteristic aza-propellane core and spirocycle structure. In this review, total syntheses of (−)-actumine A are described, focusing on the construction of above-mentioned structure.