有機合成化学協会誌
Online ISSN : 1883-6526
Print ISSN : 0037-9980
ISSN-L : 0037-9980
総説および総合論文
特許および工業化検討事例から見たフロー·マイクロ合成の技術開発動向
松本 努
著者情報
ジャーナル 認証あり

2015 年 73 巻 5 号 p. 512-520

詳細
抄録

Attention to microreactors and flow reaction technologies, in both academia and industry, has noticeably increased over the past decade. Although a large number of chemical reactions suitable for microstructured devices have been reported, there still exists a gap between laboratory and production scale. This review focuses on the use of microreactors in synthetic organic chemistry, aiming toward the production of chemical and pharmaceutical entities, through a survey of patents and other open information. The global movement of microreaction technologies is also discussed, from a viewpoint of the number of research articles and patent applications published worldwide. The goal of the present review is to provide an overview of the process development and scale-up studies in the fine chemical and pharmaceutical industries, and to illustrate an outlook for continuous-flow manufacturing as a cost effective, safe, green, and sustainable production method.

著者関連情報
© 2015 社団法人 有機合成化学協会
前の記事 次の記事
feedback
Top