フッ素原子のポイント導入による触媒反応の位置および立体選択性の制御

抄録

Organofluorine compounds are utilized for pharmaceuticals, agrochemicals, materials, and polymers. On the other hand, they play significant roles in organic synthesis, such as solvents, additives, and catalysts. Recently, it is reported that fluorine atoms can stabilize the conformers of organic molecules and even change the parent compounds’ conformations by stereoelectronic effects. Therefore directing groups or catalysts in regio- or enantioselective reactions have been improved by fluorine atoms incorporated in the molecular designs.