有機合成化学協会誌
Online ISSN : 1883-6526
Print ISSN : 0037-9980
Review de Debut
高酸化型カルデノライドの効率的合成
溝口 玄樹
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ジャーナル オープンアクセス

2017 年 75 巻 3 号 p. 253-254

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Polyoxygenated steroids cardenolides, typified by ouabagenin, possess a broad spectrum of biological activity such as inotropic activity. Due to their unique structure, including unusual cis-fused A/B- and C/D ring junction, and a number of β-configured oxygenated functional group, they have been an attractive target in chemical synthesis. In this review, recent developments in the practical synthetic strategies toward these cardenolides are described.

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© 2017 社団法人 有機合成化学協会
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