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有機合成化学協会誌
Vol. 75 (2017) No. 3 p. 253-254

記事言語:

http://doi.org/10.5059/yukigoseikyokaishi.75.253

Review de Debut

Polyoxygenated steroids cardenolides, typified by ouabagenin, possess a broad spectrum of biological activity such as inotropic activity. Due to their unique structure, including unusual cis-fused A/B- and C/D ring junction, and a number of β-configured oxygenated functional group, they have been an attractive target in chemical synthesis. In this review, recent developments in the practical synthetic strategies toward these cardenolides are described.

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