Metal free reactions by using organocatalysts were interested in the view point of green chemistry. On the other hand, a lot of Frustrated Lewis Pairs (FLPs) catalyzed reactions were reported because of its powerful potential to activate hydrogen molecule reversible. Recently, metal free C-H borylation reactions were achieved by application of amine-borane type of FLP catalysts. These methods should be alternative functionalization reactions to synthesize useful building blocks and drug derivatives.
2017 社団法人 有機合成化学協会