総説および総合論文
メソジオールの非対称化反応の最近の進展
2018 年 76 巻 8 号 p. 810-819
詳細
2018 年 76 巻 8 号 p. 810-819
The desymmetrization of meso compounds is one of the most effective strategies for asymmetric synthesis. We introduce the current progress of this area, which covers the methods for (1) enzymatic acylation of meso-diols and the hydrolysis of meso-diesters, acylation, related reactions of meso-diols with organocatalysts and metal catalysts, (2) oxidation of meso-diols by enzymes, organocatalysts, and metal catalysts. The tandem reactions based on the desymmetrization of meso-diols is also included.
