2018 年 76 巻 9 号 p. 954-955
Recently, introduction of fluorine atoms to pharmaceuticals, agrochemicals and materials has attracted much attention. Although a lot of fluorination reactions of carbonyl compounds have been developed, the number of β-fluorinations of carbonyl compounds is limited. Generally, activation of C-H bond at β-position of carbonyl group is not so easy and synthesis of β-fluorocarbonyl compounds is challenging. Herein, recent reports for syntheses of β-fluorocarbonyl compounds using transition metal catalysis are highlighted.