有機合成化学協会誌
Online ISSN : 1883-6526
Print ISSN : 0037-9980
ISSN-L : 0037-9980
Review de Debut
β-フッ素化カルボニル化合物の合成
宮川 雅道
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ジャーナル オープンアクセス

2018 年 76 巻 9 号 p. 954-955

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Recently, introduction of fluorine atoms to pharmaceuticals, agrochemicals and materials has attracted much attention. Although a lot of fluorination reactions of carbonyl compounds have been developed, the number of β-fluorinations of carbonyl compounds is limited. Generally, activation of C-H bond at β-position of carbonyl group is not so easy and synthesis of β-fluorocarbonyl compounds is challenging. Herein, recent reports for syntheses of β-fluorocarbonyl compounds using transition metal catalysis are highlighted.

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