2019 年 77 巻 1 号 p. 69-70
Transition-metal catalyzed C(sp3)-H functionalization is one of the most attractive reaction because it enables straightforward and economical syntheses of organic compounds. In the past decades, C(sp3)-H functionalization approaches using directing groups have been developed, however, their stoichiometric installation and removal of directing groups limit efficiency. Recently, a “transient directing group” strategy has been emerged as the solution of this program. This review highlights recent advances in C(sp3)-H arylation using a “transient directing group”.