2019 年 77 巻 4 号 p. 341-350
Since a cyano group can be transformed to carboxylic acids, amino- and hydroxymethyl groups as well as aldehydes, its installation, particularly catalytic protocol, has been one of the challenging issues in synthetic chemistry. Hydrocyanation of non-activated C-C multiple bonds has been one of the most powerful methods to install a CN group although selectivity control in products has been major challenge because simple olefin such as styrene derivatives is the only substrate to give higher regioselectivity in HCN addition process. In this review, the authors summarize.