Review de Debut
DNA encoded libraryの多様性拡大を指向した有機合成
2020 年 78 巻 8 号 p. 813-815
詳細
2020 年 78 巻 8 号 p. 813-815
DNA encoded library (DEL) has emerged as a widely utilized chemical library, possessing DNA-tag on each compound, for discovering hit compounds in drug discovery. However, synthetic methods for DEL are not fully exploited due to the difficulty in chemical transformation of DNA encoded compounds. This mini-review focuses on the recent development on organic synthesis for diversity expansion of DEL.
