ヘキサヒドロインダン骨格をPrivileged Structureとする酸化型テルペノイドの合成

抄録

Hexahydroindane scaffold can be found in the oxy-functionalized terpenoids such as cardiotonic steroids and picrotoxane sesquiterpenoids as a privileged structure for their biological activities. To clarify their novel functions, we have synthesized cardiotonic steroids, a pheromonal steroid, and picrotoxane sesquiterpenoid. In this publication, details of the synthetic studies on these naturally occurring products and related analogues are described, starting from tricyclic lactone as a new chiral building block.

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