アセナ7テン誘導体の合成に関する研究(第7報)
3-および4-ペンゾイルー7H-ペンツイミダゾ〔2,1a〕ベンツ(de)イソキノリン-7-オンの合成
1962 年 20 巻 11 号 p. 1016-1022
詳細
1962 年 20 巻 11 号 p. 1016-1022
In order to investigate the rate of formation of two kinds of isomer of 4-benzoyl-1, 8-naphthoylenebenzimidazole, obtained from condensation of 4-benzoylnaphthalic anhydride and o-phenylenediamine, synthesis of each of them has been made. 4-Nitro-7 H-benzimidazo [2, 1a] benz (de) isoquinoline-7-on was made through 5-nitro-8-bromo-l-naphthoic acid as a starting material, this was treated for nitrile formation by the reduction, its carboxylation and benzoylation gave 4-benzoyl compound in clear yellow plates with mp. 198-9°c. 3-Benzoyl compound was prepared from condensation of 4-nitronaphthalic anhy dride and o-phenylenediamine in almost a pure form of 3-nitro compound, and this was derived into 3-benzoyl compound in the procedure as above. 3-Benzoyl compound was clear yellow needles with mp 235-6°c.
