グアニル-o-アルキルイソ尿素(第2報)

銅触媒によるグアニル-o-アルキルイソ尿素銅錯塩およびその塩の合成

抄録

An addition reaction of alcohol on dicyandiamide in the presence of copper salt catalyst has been investigated. Guanyl-o-alkylisourea copper complex salt was synthesized with quantitative yield. By removing the copper from this complex copper salt, its salt was prepared with good yield. A high yield of guanyl-o-alkylisourea salt, which could not have been obtained when the acid catalyst was used, was investigated. Some guanyl-o-alkylisourea salts were newly prepared. By using of any desired copper salt and alcohol in the copper catalyst method, it is possible to obtain corresponding guanyl-o-alkylisourea salteasily. Therefore this method is considered to be a very convenient method for general synthesis of guanyl-o-alkylisourea salt, The mechanism of the formation of guanyl-o-alkylisourea copper complex salt was proposed by assuming of the formation of dicyandiamide coppr complex salt as the inital intermediate of this reaction.