アンブレットムスクの新合成法

抄録

Ambrette musk has a chemical structure of 2, 4-dinitro-6-t-butyl-1-anisole and elegant musk-like aroma. The usual method of its synthesis is as follows; cresol is used as a raw material, its phenolic hydroxyl group is converted into a methoxy group, then t-butyl group is introduced, and finally two nitro groups are introduced The author tried to introduce t-butyl group in m-cresol at first, and then convert the phenolic hydroxyl group into methoxy group and finally to introduce two nitro groups, and then succeeded to produce ambrette musk with good yield. A new synthetic procedure having many advantages for present process was thus established.