ニトロフラン環含有不飽和カルボン酸に対するジアゾメタンの1,3-双極性付加反応

ヘテロ芳香族性の研究 (第13報)

抄録

1, 3-Dipolar cycloaddition reaction of diazomethane with 5-nitro-2-furylacrylic acid gave 4- (5'-nitro-2'-furyl) -3-carbomethoxypyrazoline (3), mp 184485°C, in 80% yield. A similar reaction with 5-nitro-2-furylpropiolic acid afforded the corresponding isomeric mixture of the 2-pyrazole derivatives in 25% yield. (1) was refluxed in toluene to afford 2- (5'-nitro-2'-furyl) -cyclopropane carboxylate, mp 144 145°C, in 88% yield.