1980 年 38 巻 6 号 p. 538-545
In Japan, almost 80 % of annual consumption of sugar is depend on import. On this account, the technique for production of such sweetenings as millet jelly and glucose from starch have long been developed.
Since the saccharification of starch by enzymes was introduced in 1959, the isomerization of glucose to fructose have been seriously studied for the new application of glucose.
Under the situations, author began to study on the enzymatic method of isomerization of glucose to fructose and succeeded in developing first in the world an industrial production technique of glucose isomerase in 1966.
At present, the technique is being developed on a world-wide scale. In Japan, the present production of fructose syrup amounts to about 10 % of the total sugar consumption and is expected to develop further in the future.
In the present literature, the process of development of the enzyme and present status of the technique were described.