1981 年 39 巻 9 号 p. 860-861
The reactions of γ-thiobutyrolactone with primary amines (methylamine, butylamine, octylamine, aniline) afforded corresponding 4-mercaptobutanamides in 50%, 76%, 86%, 82% yield, respectively. The reactions with secondary amines (morpholine, pyrrolidine, diethylamine) also afforded corresponding 4-mercaptobutanamides in high yields, respectively. Furthermore, the reaction of two equivalents of 1-thiobutyrolactone with ethylenediamine gave N, N'-ethylenedi-4-mercaptobutanamide in 64 % yield. The mercapto compounds thus obtained were oxidized to the corresponding disulfides by dimethyl sulfoxide.