アデニン環の開裂と再閉環

抄録

Recent studies on the ring-opening and recyclization reactions of adenine and its derivatives are reviewed with particular emphasis on the synthetic utility of these transformations. Among the reactions included are Bamberger-type fission, Dimroth rearrangement of 1-alkyladenines, basecatalyzed ring-opening of 1-alkoxyadenines and N⁶, N⁶, 3, 9-tetraalkyladenines, recyclization and deformylation of the resulting ring-opened derivatives, synthetic reactions utilizing the ring-opened compounds, and ring-opening and recyclization of N^x, N^y-disubstituted adenines. Examples from the nucleoside and nucleotide series are also summarized.