4H-シクロペンタ [def] フェナントレン

その合成と反応

抄録

4H-Cyclopenta [def] phenanthrene (1) is an interesting polycyclic aromatic hydrocarbon having active methylene group. Recently, 1 attracts attention in the field of environmental chemistry because some of the derivatives show mutagenic activity. This paper deals with the syntheses and reactivities of 1 and related compounds, which are classified into reaction on the active methylene, electrophilic substitution, and reaction of the fairly localized 8-9 double bond, from the viewpoint of 1) occurrence and bioactivity, spectral characterization ; 2) synthesis of frame ; 3) reaction at active methylene ; 4) electrophilic substitution ; 5) oxidation and reduction, and the related reactions.