抄録
Rapid advances in the fields of peptide chemistry and gene technology have resulted in an explosive accumulation of structural information on not only regulatory peptides but also their biosynthetic precursors and functional proteins such as enzyme, receptor protein, oncogene product and virus protein. For understanding the physiological systems in which the peptides and proteins are involved, well-characterized and purposely designed synthetic peptides are the most important and indispensable substrates. Synthetic replicates of regulatory peptides and their analogs and synthetic fragments of functional proteins have been prepared by chemical synthesis according to either classic or solid phase techniques. In this chapter, recent advances in the fields of peptide synthesis are described.
