1988 年 46 巻 6 号 p. 596-609
Several synthetic methods of 1, 3-dioxin-4-one and its derivatives are described. These dioxinones undergo cycloreversion to formyl- or acylketenes, whose inter- or intramolecular trappings provide efficient routes to a variety of heterocycles. Use of 6-unsubstituted dioxinones in de Mayo reaction provides an efficient method for simultaneous introduction of acetic acid and formyl appendages at the vicinal position of alkanes. Recent synthesis of chiral spirocyclic dioxinones as well as their use in asymmetric synthesis are also described.