1990 年 48 巻 8 号 p. 710-723
Typical utility of carbene and carbenoid reactions is the carbon-carbon bond forming reaction which provides a number of convenient and direct tools for molecular construction by manipulating divalent and ambiphilic, , particularly electrophilic nature of carbene-type reactive molecules under controlled conditions.
The present review deals with the following topics of carbene reactions reported during 1986-1989, selected mainly from a synthetic viewpoint : (1) vinylcarbenes in equilibrium with cyclopropenes and their addition reactions, (2) carbenes substituted by hetero atom(s) such as O, N, P, and S, (3) electrophilicity of carbenoids and their stereoselective alkylation, (4) mechanism and synthetic application of C-H insertion reactions by carbenes (e.g. alkylidenecarbenes) and carbenoids (e.g. lithium (phenylthio) carbenoid), (5) rhodium-catalyzed reactions of ketocarbenoid with O-H, and N-H bond, (6) novel methods of generating carbenes under neutral and mild conditions.